We have demonstrated here that cytoplasmic inclusions of mutant SOD1 were immune-positive for two reliable stress granule markers G3BP1 [31, 32] and TIA1 in the G93A mutant SOD1 transgenic mouse spinal cord (Fig. 1a, Supplemental Fig. 1), fibroblast cells derived from human ALS patient (Fig. 1c, Supplemental Fig. 3), and cultured cells (Fig. 1d, Supplemental Figs. 4, 5). The gene discussed is G3BP1; the disease is amyotrophic lateral sclerosis.