For example, anaplastic lymphoma receptor tyrosine kinase (ALK) gene rearrangement occurs in around 5 % of NSCLC cases [1], and is detected by several methods, including fluorescence in situ hybridization (FISH), immunohistochemistry (IHC), quantitative polymerase chain reaction (qPCR), next generation sequencing (NGS), and reverse transcription polymerase chain reaction of cDNA (RT-PCR) [2]. This evidence concerns the gene ALK and non-small cell lung carcinoma.