Although PRMT5 and p44 are ubiquitously expressed in all cancer cells [29, 31, 33, 50], we observed heterogeneous expression of ErbB2, ErbB3, and FGFR3 in lung cancer cells and of some PRMT5/p44-target genes in various cancer cell lines in response to p44 silencing. This evidence concerns the gene ERBB2 and cancer.