The binding of EpCAM-positive leucocytes was very constant in a range of 5 to 10 per wire resulting in a relation of captured CTCs to leukocytes of 50% (5 leucocytes and 5 CTCs) in localized PCa and about 94.6% (5 leucocytes and 89 CTCs) in metastatic PCa patients. This evidence concerns the gene EPCAM and posterior cortical atrophy.