The paper by Stuart et al., 2012, states that a number of Hsp60 peptide epitopes that can bind multiple allelic variants of the human major histocompatibility complex molecule HLA-DR are called pan-DR epitopes which can induce low peptide-specific proliferative responses and peptide-specific production of intracellular cytokines such as interleukin-10 (IL-10), an anti-inflammatory cytokine, and interferon-γ (IFN-γ) in Type 1 diabetes [26]. Here, HSPD1 is linked to type 1 diabetes mellitus.