A diagnosis of systemic lupus erythematosus (SLE) was made based on the following SLICC criteria: arthritis, proteinuria, hemolytic anemia with a positive direct antiglobulin test after recovering from the sepsis, lymphopenia, high-titer ANA by ELISA and Hep2-cells, and repeatedly positive anti-dsDNA. The gene discussed is BTG3; the disease is systemic lupus erythematosus.