Third, in terms of GDM, it was also found that the prevalence of GDM was also the highest in Asian ethnicity, and although it was very difficult to compare the proportion of GDM patients that need insulin therapy across from different regions, limited data did support that there were great variations among different ethnicities; for example, women with GDM from southeast Asia had the lowest prevalence of insulin therapy (37.2%), while Anglo-Europeans has the highest (56.7%) [10, 11]. This evidence concerns the gene INS and gestational diabetes.