To validate the impact of AAGUGC-miRNA expression on cell proliferation and EGFR-TKI sensitivity, four different lung cancer cell lines (U1810, A549, NCI-H1703 and SK-MES-1) were stably transduced with a hsa-mir-372 (hereafter refered to as miR-372) expression vector or a control vector. The gene discussed is EGFR; the disease is lung cancer.