Likewise, oncogenic MYC signaling would result in inhibition of the same TSs through transcription of other oncomotif-miRNAs (hsa-mir-17 and hsa-mir-20a).19 The fact that hsa-mir-93 and hsa-mir-17 are the dominant oncomotif-miRNAs in most cancer cases suggests that oncogene-dependent transcription through MYC and E2Fs is an important contributor to oncomotif-miRNA expression in cancer, but the elucidation of specific mechanisms of oncomotif-miRNA expression in different cancer types warrants further investigation. This evidence concerns the gene MYC and cancer.