GAD1 and colorectal carcinoma: The CRC gene collection was mainly based on five data sources (Fig. 1A), including OMIM (Online Mendelian Inheritance in Man)8, GAD (The Genetic Association database)9, genes manually curated from GeneRif10, genome-wide association studies from GWASCatalog11 and meta-analyses results of genetic association studies from the CRCGene database (http://www.cphs.mvm.ed.ac.uk/projects/CRCgene/index.php).