KNL1 and breast cancer: With overexpression of hCINAP, mRNAs encoding oncogenes Myc, SNCG (γ-synuclein), which increases metastasis and promotes genetic instability in breast cancer, CASC5 (cancer susceptibility candidate 5), as well as VOPP1 (vesicular overexpressed in cancer, prosurvival protein 1) were strongly shifted to the polysome fractions, indicating active translation (Fig. 7f).