AK6 and neoplasm: As the critical role of hCINAP in regulating tumour cell growth, to determine whether hCINAP is required for tumorigenesis in vivo, HCT116 cells with stably expressed hCINAP-shRNA or control-shRNA were injected subcutaneously into the right flank of nude mouse, after which tumour growth was monitored for 3 weeks.