In contrast to CD10+/CD20+ germinal center B cells,11 proliferation rates in the T-cell areas of mucosa-associated lymphoid tissue (MALT) were similar between patients with PHTS and control subjects, and the apoptosis rate of CD3+ T lymphocytes in situ was comparatively low (see Fig E4, A and B, in this article's Online Repository at www.jacionline.org). The gene discussed is MME; the disease is PTEN hamartoma tumor syndrome.