CRMP1 and metastatic malignant neoplasm in the lymph nodes: The functional difference between CRMP1 and LCRMP1 has previously been investigated in non-small-cell lung cancer (NSCLC) [16, 17] Low CRMP1 mRNA expression in lung cancer tissue was significantly associated with advanced disease, lymph node metastasis, early post-operative relapse, and shorter survival [17].