Within 8 days of infection, multiple fates emerged including a dominant population of MSP1+CD138+ PBs that primarily expressed IgM as measured by flow cytometry and serum ELISA consistent with previous reports (Achtman et al., 2003, Nduati et al., 2010) (Figures 2A, S3A, S3D). The gene discussed is CD40LG; the disease is infection.