For all T-cell phenotypes, the mean number of infiltrating cells per high power field (HPF) was significantly higher in the invasive margin (CD3: 306.93 ± 203.32; CD8: 149.37 ± 108.68; FoxP3: 20.26 ± 26.72; CD3-zeta: 98.93 ± 103.09) than in the tumor center (CD3: 126.81 ± 119.35; CD8: 82.84 ± 83.86; FoxP3: 14.90 ± 25.47; CD3-zeta: 31.11 ± 52.32; p < 0.0001). This evidence concerns the gene FOXP3 and neoplasm.