RETN and Insulin resistance: Conversely, Pangaribuan et al. [22] found that none of the 24 PCOS patients in their study presented hyperesistinemia, there was no significant difference in serum resistin concentration between PCOS group and controls, and there was no correlation with BMI and HOMA-IR; instead, they showed that lower adiponectin level was associated with insulin resistance and BMI in PCOS women.