Research led by Bota indicated that the serum PCT level was not significantly lower in patients with hepatic cirrhosis than in other patients without cirrhosis.[11] A few studies have evaluated the diagnostic value of PCT in patients with liver diseases, and some of these suggested that PCT was not an accurate marker of SBP in cirrhotic patients,[12] and the cut-off values for prediction of infections were highly variable.[13–16] However, no study has assessed the relationship between decreased liver function and serum PCT concentration. The gene discussed is CALCA; the disease is liver disorder.