A recently published study indicated that in patients with various forms of acute liver failure, PCT appeared to correlate with aminotransferase levels.[33] That study included patients with acute liver failure, who often have higher alanine aminotransferase (ALT), aspartate aminotransferase (AST), and endotoxin levels in the early stage than in chronic liver disease. The gene discussed is CALCA; the disease is acute liver failure.