PPIB and cholesteryl ester measurement: Interestingly, cyclophilins were also detected by immunological screening of a cDNA library from the zoonotic cestode Echinococcus granulosus, causing cystic echinococcosis (CE), with sera from infected human subjects that had displayed allergic (skin) reactions [48]; sera from these patients did not recognise the homologous human cyclophilins, nor that from the yeast Malassezia furfur, thus supporting the hypothesis that the parasite cyclophilin was responsible for the allergic reactions observed in patients with CE [48].