MAP3K8 and infection: Further analysis of the T cell receptor signaling pathway revealed two other significant changes in phosphorylation events: (1) phospholipase C-γ1 (PLCG1) was significantly dephosphorylated in the S. Enteritidis-infected cecal tissue at four days post-infection when compared to the non-infected control cecal tissue; and (2) a significant dephosphorylation of MAPKs, including MEK1, ERK1, MAP3K8, and p38.