The transcript levels of the M2 macrophage markers Cd206, Cd163, Il4ra were all increased, whereas the levels of M2 markers Fizz1 and Ym1, were decreased in the tumor-infiltrating myeloid cells following Vorinostat, suggesting a mixed M1/M2 macrophage phenotype (Fig. 6A). This evidence concerns the gene IL4R and neoplasm.