More than 20 mutated podocyte genes, including the transient receptor potential canonical channels type 6 gene (TRPC6), the alpha‐actinin‐4 gene (ACTN4), the CD2‐associated protein gene (CD2AP), the inverted formin 2 gene (INF2), the nephrin gene (NPHS1), the NPHS2 podocin gene (NPHS2), the Wilms tumour 1 gene (WT1) and the Rho GTPase‐activating protein 24 gene (ARHGAP24), have been identified to cause familial FSGS 6. This evidence concerns the gene INF2 and focal segmental glomerulosclerosis.