EZH2 and immune system disorder: We have previously shown that EZH2 has critical roles in regulating the T-cell response in several immune diseases.9, 17, 18 Given that EZH2's function and target genes largely depend on its interacting proteins, we sought to reveal a new EZH2 regulatory pathway by identifying new EZH2-interacting proteins in T cells, in hopes of facilitating the development of new drug targets for treating immune diseases.