GZMB and breast carcinoma: Additionally, Piotrowska et al. demonstrated in Hut-78 and Raji B-lymphoma cells, MCF-7 breast cancer cells, and HT-29 colon carcinoma cells that known growth inhibitors trichostatin, sodium butyrate, and 5-Aza-20-deoxycytidine treatment suppressed GRβ and enhanced GRα with an increase in GC sensitivity [28, 29].