2011; Ambalavanan et al. 2015). Childhood onset schizophrenia (COS) is a rare disorder where children over the age of 7 begin to experience schizophrenic symptoms. To date no investigation into variations in RTN4R have been performed in a COS population but intriguingly, 6% of COS patients carry the 22q11 deletion. Here, RTN4R is linked to schizophrenia.