Despite apparently diminished basal IFN-γ responses during malnutrition, however, mice vaccinated with the Salmonella enterica serovar Typhi strain CVD 908-htr intranasal vector expressing the Cryptosporidium sporozoite antigen Cp15 [25] had unexpectedly preserved splenocyte CMI, including IFN-γ recall responses, through two weeks post vaccination [26]. This evidence concerns the gene IFNG and nutritional deficiency disease.