Sm16/SPO-1 has been implicated in inducing the anti-inflammatory cytokine, IL-10 and thus involved in host immunomodulation [74], while, as its name suggests, FABP/Sm14 plays an important role in the binding and transport of lipids and is being developed as a schistosomiasis vaccine candidate [75, 76]. The gene discussed is IL10; the disease is schistosomiasis.