Finally, we detected no significant interaction between genetic factors (CFH rs1061170, ARMS2 rs10490924, LPL rs12678919 and LIPC rs493258 polymorphisms) and consumption of olive oil (all p>0.05) for early AMD models and no interactions for late AMD models (except for LIPC and LPL in late AMD models, due to insufficient power, the test of interactions for those two genes were non applicable). The gene discussed is LIPC; the disease is age-related macular degeneration.