Previously, Chen at al attempted to show improved tumor killing using co-culture system with HCC827 as target tumor cells and peripheral blood mononucleate cells (PMBC) from random donor and did not observed improved tumor killing by alloreactive T cells when a combination therapy with PD-1/PD-L1 blockade and EGFR inhibitors was used [20]. The gene discussed is EGFR; the disease is neoplasm.