As expected, PD-L1high lung cancer cell lines were more sensitive to the inhibition of EGFR signaling pathway compared to PD-L1low lung cancer cell lines, and the inverse correlation was observed between overexpression of PD-L1 and IC50 value (Pearson’s correlation coefficient r = -0.2113, p = 0.0443,Table 3). The gene discussed is EGFR; the disease is lung cancer.