In addition, we sought to evaluate the HOTAIR expression level in cervical cancer tissues and observed that HOTAIR expression level was increased in 72.5%, was unchanged in 8.8%, or was decreased in 18.7% of cervical cancer tissues compared with adjacent tissues (P<0.05) (Fig 1E), suggesting that the expression of HOTAIR is upregulated in cervical cancer. This evidence concerns the gene HOTAIR and cervical carcinoma.