In this study, various differentially expressed lncRNAs were identified that appear to regulate target protein-coding genes that are closely associated with NASH, such as PPAR alpha, HMGCS2, FADS2, DGAT2, ACAA2, CYP2E1, ADH4, and Fos. The gene discussed is HMGCS2; the disease is metabolic dysfunction-associated steatohepatitis.