CD4 and lymphoma: Since we have demonstrated that immunoliposomes with covalently grafted anti-CD4 Vhhs facilitated cellular uptake of liposomes by lymphoma cells overexpressing CD4 on the surface (data not shown), it follows that a combined liposome platform encapsulating dapivirine with non-covalently attached J3 and covalently linked anti-CD4 Vhh could be a powerful potential candidate for HIV prevention where J3 neutralizes free virus and dissociates from liposome while the anti-CD4 Vhh coated liposome efficiently delivers the antiviral drug to HIV target cells overexpressing CD4.