Studies found that ferulic acid (FA) could improve neurological function and decrease infarction size in middle cerebral artery occlusion (MCAo) rats through anti-oxidative and anti-inflammatory effects, and it could also advance angiogenesis via increasing vascular endothelial growth factor (VEGF), platelet-derived growth factor and hypoxic-induced factor (HIF)-1α expressions in human umbilical vein endothelial cells [13, 14]. Here, VEGFA is linked to infarction.