ERBB2 and breast carcinoma: We identified pathways that are modulated by exogenous palmitate in the HER2/neu-positive SKBR3 breast cancer cell line and compared this response to that of HER2-normal MCF7 breast cancer cells, which have previously been shown to respond to exogenous palmitate in a way that is comparable to non-tumorigenic MCF10A mammary epithelial cells or normal human mammary epithelial cells (HMECs) [7, 26].