Additionally, analysis of molecular profiling data sets of invasive breast carcinomas generated by the TCGA Research Network [1] revealed an association between the ER stress markers and the HER2/neu, NR1D1 and PBP genes linked to lipogenesis [6–9, 19] in human breast tumors (Additional file 1: Figure S8). This evidence concerns the gene NR1D1 and invasive breast carcinoma.