Immunohistochemical analysis of the tumor regions revealed low-intensity p85 expression in the p42-AV and p42 (183–394 and 280–394 aa)-AV injection groups, than that of control or p48-AV injected group, with less frequent expression of proliferating cell nuclear antigen (PCNA) (Fig. 7d). This evidence concerns the gene PCNA and neoplasm.