CTLA4 and neoplasm: We observed a strong overexpression, in both the tumor-near stroma and the tumor (measured as fold-change, X and range) of CD25 (19.46X, [2.7-86.0], 11.59X, [0.3-54.2]), FOXP3 (4.96X, [0.2-67.4], 4.08X, [0.1-38.0]), CTLA4 (2.89X, [0.2-65.7], 3.02X, [0.1-59.8]) and TGFB1 (3.24X, [0.6-16-6], 2.117X, [0.2-27.2]).