Moreover, patients with high infiltration of FOXP3+ cells in the stroma and low infiltration of CD8+ in the tumor also presented inferior PFS (15.3 vs. 35.9 months, p = 0.035) and OS (17.4 vs. 68.8 months, p = 0.011; Figure 4C-4D; Table 2). Here, CD8A is linked to neoplasm.