Furthermore, no significant correlation was observed between the plasma miR-224 levels and other clinical indicators, such as the tumor makers PIVKA-II (DCP) and AFP, the ICG retention rate (ICG 15R), total bilirubin (T-Bil), albumin(Alb), prothrombin time (PT (%)), aspartate transaminase (AST) and alanine transaminase (ALT) (Figure 6). Here, F2 is linked to neoplasm.