By analyzing the comprehensive RNA-seq data for nine types of cancers that were derived from the paired normal controls and tumors and were unrestrictedly available in the TCGA database (http://cancergenome.nih.gov/), we found that UHRF1 is universally overexpressed in all nine types of cancers (Figure 5c), whereas UHRF2 is overexpressed in some but not in all cancers (Figure 5c). This evidence concerns the gene UHRF2 and cancer.