UHRF1 and cancer: By analyzing the comprehensive RNA-seq data for nine types of cancers that were derived from the paired normal controls and tumors and were unrestrictedly available in the TCGA database (http://cancergenome.nih.gov/), we found that UHRF1 is universally overexpressed in all nine types of cancers (Figure 5c), whereas UHRF2 is overexpressed in some but not in all cancers (Figure 5c).