Despite a difference of 20 days for disease onset, mice that succumbed earlier to Trib2−/− T-ALL had a similar degree of leukemic burden (Figure 5d and e) but exhibited a trend of higher organ infiltration of leukemic cells (Figure 5f) compared with mice that succumbed to WT T-ALL. This evidence concerns the gene TRIB2 and acute lymphoblastic leukemia.