DISC1 and schizophrenia: Moreover, dysbindin-1B interacts with Snapin, another component of biogenesis of lysosome related organelles comple-1 complex in vitro (Supplementary Figure S6A), and recruits Snapin to agrresome in COS1 cells (Supplementary Figure S6B), implying dysbindin-1B interfer dysbindin-1A function by disrupting its interaction with partners such as DISC1 or snapin, or by impairing neurite outgrowth or neurotransmitter transport, which may have a role in the pathogenesis of schizophrenia.