SHBG and type 2 diabetes mellitus: Because SHBG is inversely related to BMI beginning in childhood, and is a marker for insulin resistance and the risk for developing T2DM [1], we hypothesized that SHBG levels at birth might represent a biomarker of fetal metabolic status, and might be related to the newborn’s Ponderal index or skin fold thickness, or might correlate with maternal obesity or pregnancy weight gain.