For example, although no direct association has been reported for the P08727 protein (asthma biomarker) and Tenecteplase (drug), an indirect relationship can be identified between these two entities given that the P05787 protein (KRT8 gene) has sequence similarity with the P08727 protein, which was reported as a target for Tenecteplase, (Fig. 7). The gene discussed is KRT19; the disease is asthma.