Given that one HF-induced DEG with at least twofold difference between FHF vs. FC was Agtr1b (fold change [FC] = 4.37) (Figure 3A), and that RAS is involved in programmed hypertension, we next investigated components of RAS to elucidate underlying mechanisms related to programmed hypertension. The gene discussed is AGTR1; the disease is hydrops fetalis.