Levels of urinary L-FABP in each DKD group differed significantly from levels in the other groups and increased markedly in accordance with the severity of DKD (P = 0.000 between three groups; DKD patients with microalbuminuria compared with DM patients with normoalbuminuria P = 0.002; DKD patients with macroalbuminuria compared with DM patients with normoalbuminuria P = 0.000; DKD patients with macroalbuminuria compared with DM patients with microalbuminuria P = 0.005, respectively) (Table 4). This evidence concerns the gene FABP1 and diabetic kidney disease.