MCT1, CD147 and GLUT1 positivity were positively associated in CRC and lymph node metastasis, although the expression of MCT1 was less pronounced in the metastasis than the primary tumour, which suggests that metabolic profile of the lymph node metastasis may be different from the primary tumour. Here, SLC2A1 is linked to metastatic malignant neoplasm in the lymph nodes.