We also matched the expression of these metabolism-related proteins in CRC hepatic metastasis with NA hepatic tissue, and we observed that these proteins presented a low expression in the liver tissue (p < 0.001, for all proteins, data not shown), namely MCT4 and GLUT1 with no expression and MCT1 and CD147 with 64.4 and 30 %, respectively, at NA hepatic tissue. The gene discussed is SLC2A1; the disease is colorectal carcinoma.