Compared to the MCTs expressions, the percentage of CD147 and GLUT1 positivity reactions were lower in CRC primary tumour; however, there was an increase in their expression from CRC primary tumour to lymph node (p < 0.001 and p = 0.003, respectively) and hepatic metastasis (p < 0.001, for both) (Fig. 2). This evidence concerns the gene SLC2A1 and neoplasm.