A variety of ALK partner genes have been subsequently identified in IMT owing to diverse chromosomal rearrangements, including TPM3 at 1p23, TPM4 at 19p13, CLTC at 17q23, CARS at 11p15, ATIC at 2q35, SEC31L1 at 4q21, PPFIBP1 at 12p11 and ran-binding protein 2 (RANBP2) at 2q13 [13–17]. The gene discussed is TPM3; the disease is inflammatory myofibroblastic tumor.