Galectins 1, -2, -4, -7, -8 and -9 are expressed in human brain [13] and Galectin-1, Galectin-3 (Gal-3) and Galectin-8 (Gal-8) are the most abundantly expressed in human glioma cell lines [14]. Here, LGALS8 is linked to central nervous system cancer.