Infection with NL4-3 ΔNF-κB1,B2, compared to wild type NL4-3, showed a decreased in HIV integration to undetectable levels in all 4 donors by a mean (range) of 40 (1–115.4) fold (p = 0.03) in CCL19-treated CD4+ T cells with only a modest reduction in HIV integration of 5 (1.7–11) fold in fully activated CD4+ T cells although this was not significant. The gene discussed is CCL19; the disease is infection.