MAPT and Alzheimer disease: After adjustment for following covariates: gender, age, and education the concentrations (mean with SE) of Tau and p-Tau181 were significantly higher in AD patients (Tau 47.39±1.34 ng/μL, p-Tau181 0.157±0.005 ng/μL) as compared to that of MCI patients (Tau 39.27±1.38 ng/μL, p-Tau181 0.139±0.005 ng/μL) and elderly controls (Tau 35.02±1.31 ng/μL, p-Tau181 0.124±0.005 ng/μL).