A paired comparison of these 15 cytokines (irrespective of the treatment group) showed that 12 (eotaxin, FGF-2, IFN-γ, IL-10, IL-1Ra, IL-1α, IL-8, IP-10, MCP-1, MDC, TNF-α and sCD40L) were differentially expressed between baseline and acute phase of dengue illness (Fig 1). This evidence concerns the gene TNF and dengue disease.