We then examined its potential as a biomarker of fibrosis in two mouse models of fibrosis: mdx mice that mimic Duchenne Muscular Dystrophy (DMD), a genetic disorder caused by mutations in the dystrophin gene and associated with weakness in the diaphragm and myocardium, tissues most affected by fibrosis [3], and CCl4-induced liver fibrosis. This evidence concerns the gene DMD and Duchenne muscular dystrophy.