Indirect markers of liver fibrosis include specific transaminases or molecules such as α2-macroglobulin, apolipoprotein A1, haptoglobin, γ-glutamyl transpeptidase (GGT) and bilirubin, which are components of a common assay of liver fibrosis known as Fibrotest [30,36]. The gene discussed is APOA1; the disease is Hepatic fibrosis.