SCN1A and encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy: This is consistent with previous findings in mouse models of Dravet syndrome that correlated Nav1.1 expression and function in inhibitory interneurons (Cheah et al., 2012; Dutton et al., 2012; Ogiwara et al., 2013; Ogiwara et al., 2007; Tai et al., 2014) but differs from some of the previous findings in iPSC models (Higurashi et al., 2013; Jiao et al., 2013; Liu et al., 2016; Liu et al., 2013).